Pharmacological effect of Sanctura XR
Sanctura XR Means of reducing the tone of smooth muscles of the urinary tract. M-holinoblokator acts on the peripheral M-cholinergic receptors. Has ganglioblokiruyuschey activity. Lowers the tone of smooth muscles of the digestive tract.
Sanctura XR Dosage
At intake – 20 mg 2 times a day.
Sanctura XR Drug Interactions
While the application of enhanced anticholinergic effects of amantadine, tri-and tetracyclic antidepressants, antipsychotics, other m-holinoblokatorov, quinidine, antihistamines, disopyramide.
While the application of enhanced tachycardia caused by beta-adrenomimetikami.
Pregnancy and lactation Sanctura XR
Data about the safety of trospiya chloride during pregnancy in humans are not available, application is possible only under strict indications.
In experimental studies have found that trospy chloride crosses the placenta in limited quantities.
Side effects of Sanctura XR
From the digestive system: often – dry mouth, rarely – nausea, constipation or diarrhea, and vomiting.
With the cardiovascular system: rarely – tachycardia, arrhythmia.
CNS and peripheral nervous system: rarely – accommodation disturbances, dizziness, mydriasis, restlessness, agitation, fatigue, headache, drowsiness, or sleep disorders.
With the urinary system: rarely – urinary retention, dysuria.
Other: rarely – the suppression of secretion of sweat glands and sweating, dyspnea, allergic skin reaction in rare cases – metrorrhagia, mammalgia.
Indications Sanctura XR
Symptomatic treatment of spasm of the detrusor muscle of the bladder, including frequent urge to urinate, feeling of incomplete bladder emptying (thamuria), nocturia, and involuntary urination with or without urge.
Contra Sanctura XR
Mechanical stenosis of GIT, benign prostatic hyperplasia with severe symptoms of the presence of residual urine, as well as other state, accompanied by stenosis of the urethra, the complete and partial bowel obstruction, megacolon, glaucoma, tachyarrhythmia, myasthenia gravis, heart failure, liver damage and kidney failure, urinary tract infection the age of 18 years, increased sensitivity to trospiyu chloride.
Cautions
With careful use in prostatic hyperplasia and bladder syndrome hyperesthesia with mild symptoms of the presence of residual urine.
Effects on ability to drive vehicles and management mechanisms
It should be used with caution in patients who engaged in potentially hazardous activities that require high speed of psychomotor reactions.
